Professor
Anthony R. Means
Baylor College of Medicine
Endocrinologist; Cellular biologist; Educator
Area
Biological Sciences
Specialty
Medical Sciences
Elected
2002
Means studies how calcium/calmodulin (CaM) participate in the regulation of cell function. He was one of several investigators to independently identify CaM and is principle architect of a central tenant in biology that CaM is the primary and ubiquitous receptor for calcium. He sequenced the CaM protein, isolated its gene and determined its 3D structure in the presence of calcium and bound to two separate target protein kinases. Most recently, he discovered novel CaM kinases and generated mouse models that implicate roles for these proteins in cancer, diabetes/obesity and other components of metabolic syndrome, reproductive failure and behavioral disturbances.
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