Casey is a Professor of Psychology, member of the Justice Collaboratory in the Yale Law School and of the Interdepartmental Neuroscience Program at Yale University in addition to Visiting Investigator at The Rockefeller University. Casey is a world leader in human neuroimaging and its use in studying typical and atypical development. She uses brain imaging to examine developmental transitions across the life span, especially during the period of adolescence. Her work is grounded in translational studies from genetically altered mice to human patients. She has served on numerous advisory boards including the NIMH Board of Scientific Counselors, and National Research Council and Institute of Medicine committees of the National Academies on the Science of Adolescent Risk Taking, Assessing Juvenile Justice Reform, and Sports Related Concussions in Youth.