Brenda L. Bass
University of Utah School of Medicine
Biochemist; Molecular biologist; Educator
Biochemistry, Biophysics, and Molecular Biology
Made seminal contributions to understanding double-stranded RNAs and the proteins that act on them in metazoan cells. Discovered the enzyme ADAR (adenosine deaminase acting on RNA), established its site-specific modification of mRNA, uncovered through structural studies its obligate cofactor inositol hexakisphosphate, and demonstrated its relationship to RNA interference.