Elazer Reuven Edelman

Important figure in the development of metal stents and the creation of drug-eluting stents. Contributions to vascular biology, in particular, his work on vascular repair enabled use of antisense oligonucleotides, growth factor therapies for angiogenesis regulation, vascular tissue engineering and endovascular stenting. Research harnessing these several fields drove the preclinical development of the most successful bare metal and drug-eluting stents. The latter arose directly from his conception and first demonstration of local vascular drug delivery, and his creation of polymer-based drug delivery (US Patent 5,716,981 derived directly from Meth. Enz. 1986). Also generated pathobiologic and mathematical tools to examine cardiovascular devices that are the basis of FDA required submissions. Recipient, Hoeg Prize of the Council on Arteriosclerosis, Thrombosis, and Vascular Biology of the American heart Association.