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Dr.

Haig H. Kazazian

(
1937
–
2022
)
University of Pennsylvania
;
Baltimore, MD
Geneticist; Educator
Area
Biological Sciences
Specialty
Biochemistry, Biophysics, and Molecular Biology
Elected
2007
First to demonstrate that transposable elements cause disease in man by insertional mutagenesis. Studies documented the existence of active retrotransposons in humans and mice, suggesting active retrotransposons in all mammals. Discovered that retrotransposon mobility leads to shuffling of exons and their flanking sequences, a finding of major impact to our understanding of evolution.
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