Professor

Nicholas R. Cozzarelli

(
1938
2006
)
University of California, Berkeley
;
Berkeley, CA
Molecular biologist; Educator
Area
Biological Sciences
Specialty
Biochemistry, Biophysics, and Molecular Biology
Elected
2000
Our recent work has been on partitioning of chromosome and the mechanism of topoisomerases and helicases as well as the structure and function of topologically constrained DNA. We have studied the requisite DNA-protein interactions in vitro and the physiological roles in vivo. Enzymological, mathematical, and genetic techniques are used to develop an integrated picture of the biochemistry and physiology of these systems.
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