Norbert Perrimon

Dr. Perrimon is the James Stillman Professor of Developmental Biology at Harvard Medical School; Investigator of the Howard Hughes Medical Institute; Associate Member of the Broad Institute; and Member of the Cancer Biology and Cancer Genetics Departments of the Dana-Farber/Harvard Cancer Center. He has 30 years of experience in the fields of developmental genetics, signal transduction and genomics. His group developed many methods that have significantly improved the Drosophila toolbox and has characterized many components of signaling pathways. His group established high-throughout genome-wide RNAi screens to systematically interrogate the entire Drosophila genome in various cell-based assays. In 2003 he created the Drosophila RNAi Screening Center (DRSC) to make the technology available to the community, and in 2008 established the Transgenic RNAi Project (TRiP) to build a genome scale resource of transgenic shRNA flies. Currently, his laboratory is applying large-scale RNAi and proteomic methods to obtain a global understanding of the structure of a number of signaling pathways and their cross-talks. In addition, he is studying the roles of signaling pathways in homeostasis and tissue remodeling in Drosophila muscles and gut stem cells. Dr. Perrimon has trained more than 80 students and postdoctoral fellows, with most of them currently holding academic positions. He has been elected to the American Academy of Arts and Sciences,  American Association for the Advancement of Science,  EMBO, and National Academy of Sciences.