On January 29, 2026, the Academy’s San Diego Committee, in partnership with the San Diego Natural History Museum, organized a discussion on the importance of science in our everyday lives and its impact on our future. The program featured Rommie Amaro (University of California, San Diego) and J. Craig Venter (J. Craig Venter Institute) in conversation with Peter Cowhey (University of California, San Diego). Judy Gradwohl (San Diego Natural History Museum) and M. Margaret McKeown (U.S. Court of Appeals for the Ninth Circuit) provided welcome remarks. An edited transcript of the program follows.